01Peptides — 22 articles

Peptide Education

Peptides are the most hyped corner of wellness and the worst explained. Each guide covers the mechanism, the trials, the regulatory status in Canada, and what's still just gym talk. No dosing protocols, here or anywhere on this site.

01RetatrutideEli Lilly's three-receptor experiment posted some of the largest weight-loss numbers ever seen in a trial. It is still years from any pharmacy shelf.

Investigational (Phase 3)↗

02TirzepatideThe GIP/GLP-1 combination behind Mounjaro and Zepbound beat the first-generation drugs in a head-to-head trial.

Authorized medicine exists↗

03SemaglutideFrom a lizard-venom lineage to Ozempic and Wegovy, the best-studied GLP-1 drug has outcome data most compounds on this site can only dream about.

Authorized medicine exists↗

04TesamorelinA Montreal-born GHRH analogue earned real approval for a narrow indication, and a much broader following that the evidence doesn't yet cover.

Product- and jurisdiction-dependent↗

05CJC-1295Its corporate development ended years ago, yet this long-acting GHRH analogue lives on as a fixture of the grey-market growth hormone stack.

Unauthorized research compound↗

06IpamorelinNovo Nordisk built it, tested it, and shelved it. Its reputation for selectivity keeps it circulating two decades later.

Unauthorized research compound↗

07BPC-157Beloved by athletes and podcast hosts, backed almost entirely by rodent studies. The gap between BPC-157's reputation and its human evidence is the story.

Unauthorized research compound↗

08TB-500A fragment tied to thymosin beta-4 built a following in equine sport before migrating to gym bags. Human trial evidence is still stuck at the starting gate.

Unauthorized research compound↗

09GHK-CuIn a face cream, it's a legitimate cosmetic ingredient with decades of skin research; in a syringe, it's an entirely different, and unauthorized, proposition.

Route- and product-dependent↗

10MOTS-cEncoded in the genome of the cell's power plants, MOTS-c has made exercise scientists sit up. It remains a research story, not a product.

Unauthorized research compound↗

11NAD+The coenzyme at the heart of cellular energy declines with age; whether drips, shots, or precursor pills meaningfully change human aging is another matter.

Depends on product and route↗

12SS-31 / ElamipretideElamipretide binds a lipid found almost nowhere else in the cell. Drug developers have spent a decade betting on that.

Investigational↗

13EpitalonFour amino acids, a pineal-gland backstory, and telomere claims that have never faced a rigorous modern trial.

Unauthorized research compound↗

14SermorelinOnce an FDA-approved pediatric drug, sermorelin now lives a second life in longevity clinics. That history explains both its appeal and its ambiguity.

Regulatory history; product-dependent↗

15KPVA fragment of a melanocyte hormone has become a forum favourite for inflammatory bowel symptoms, on the strength of mouse studies alone.

Unauthorized research compound↗

16AHK-CuA copper-binding tripeptide marketed for hair growth on a fraction of the evidence its famous cousin has.

Cosmetic-interest; product-dependent↗

17KisspeptinNamed after a chocolate, discovered in a cancer lab, and now one of the most legitimately interesting peptides in clinical research.

Research and clinical development↗

18DSIPIsolated from rabbit brains in the 1970s, delta sleep-inducing peptide never reliably induced sleep. Its modern marketing leaves that part out.

Unauthorized research compound↗

19SelankA tuftsin-based nasal spray with regulatory standing in Russia and none at all in Canada.

Unauthorized in Canada↗

20SemaxStripped of its hormonal activity and stabilized against enzymes, Semax became a Russian stroke drug and, later, a Western nootropic curiosity.

Unauthorized in Canada↗

21PT-141 / BremelanotideBremelanotide is an approved prescription medicine in the US. That is exactly why the grey-market version is so misleading.

Authorized in some jurisdictions↗

22Thymosin alpha-1Thymalfasin has decades of clinical use abroad for hepatitis and immune support, and a much shakier life in the longevity market.

Jurisdiction-dependent↗

“An active ingredient can have strong evidence in an authorized medicine while a ‘research use only' vial of the same molecule remains unauthorized. Authorization attaches to the product, not the name.”

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Peptide Education

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Two minutes to read.